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Educational Background:
Areas of Research Interest: Radiopharmaceutical Chemistry. My research interests focus on the synthesis and development of positron-emitting radio-pharmaceuticals for application to positron emission tomography (PET) studies. PET has the unique ability to image biochemical and biological processes of the living human body that are fundamental to disease and understanding the normal function of various organ systems of the body. For example PET has shown to be especially useful to image neurological and psychiatric disorders, heart disease, and cancer. Selected Publications: Yee SH, Lee K, Jerabek PA, Fox PT. Quantitative measurement of oxygen metabolic rate in the rat brain using microPET imaging of briefly inhaled 15O-labelled oxygen gas. Nucl Med Commun. 2006 Jul;27(7):573-81. Yee SH, Jerabek PA, Fox PT. Non-invasive quantification of cerebral blood flow for rats by microPET imaging of 15O labelled water: the application of a cardiac time-activity curve for the tracer arterial input function. Nucl Med Commun. 2005 Oct;26(10):903-11. Feng CM, Narayana S, Lancaster JL, Jerabek PA, Arnow TL, Zhu F, Tan LH, Fox PT, Gao JH. CBF changes during brain activation: fMRI vs. PET. Neuroimage. 2004 May;22(1):443-6. Goins, B, Klipper R, Martin C, Jerabek PA, Khalvati S, Fox PT, Cliff RO, Kwasiborski V, Rudolph AS, and Phillips WT: Use of Oxygen-15-Labeled Molecular Oxygen for Oxygen Delivery Studies of Blood and Blood Substitutes. In Hudetz and Bruley (Eds.), Oxygen Transport to Tissue XX, Plenum Press, New York, Chapter 76: 643-652, 1998 Phillips WT, Goins B, Klipper R, Cook BG, Martin C, Lemen L, Jerabek PA, Khalvati S, Fox PT, Cliff RO, Kwasiborski V, and Rudolph AS: Tissue Oxygen Delivery and Tissue Distribution of Liposome Encapsulated Hemoglobin. In Tsuchida E (Ed), Present and Future Perspectives of Blood Substitutes, Elsevier Science, Lausanne, Switzerland, Chapter 12: 147-160, 1998 Contact Information: Unversity of Texas Health Science Center Phone: 210-567-8190 Fax: 210-567-8152 jerabek@uthscsa.edu |
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Paul A. Jerabek, Ph.D.