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Biomedical Engineering Faculty


Geoffrey D. Clarke, Ph.D.
Professor and Vice-Chair of Graduate Education in Radiology

Educational Background:
M.S., University of Texas Health Science Center at Dallas & University of Texas at Arlington (jointly)
Ph.D., University of Texas Health Science Center at Dallas

Areas of Research Interest:

  • Cardiovascular Imaging Physics-Magnetic resonance imaging of coronary flow and flow reserve, regional myocardial blood volume, myocardial perfusion, and vascular imaging agents - especially with regard to implications for the diabetic patient.
  • Clinical Imaging Equipment Quality Control-Procedures and programs for clinical MRI quality control and acceptance testing; development of standards and MRI phantom for quality control and accreditation.
  • Radiation Safety in Diagnostic Radiology-Reference Values for Patient Doses in Diagnostic Radiology - Patient Doses in CT Imaging. Methods for estimating dose for x-ray angiographic and cardiological imaging equipment.
  • In-vivo Magnetic Resonance Spectroscopy-P-31 myocardial MRS in a canine model of acute coronary occlusion and reperfusion; also H-1 & P-31 brain MRS in a feline model of blunt force trauma.
  • Novel MRI Methods-multiple quantum coherence imaging, parallel MRI
  • Institutional Appointments:

    • Director, Graduate Program in Radiological Sciences
    • Chair, Committee on Graduate Studies, Graduate Program in Radiological Sciences
    • Interim Director, Magnetic Resonance Division, Research Imaging Center
    • Member, Graduate Faculty Council
    • Member, MD/PhD Admissions Committee
    • Vice-Chair, Radiation Safety Committee

    Professional Service:

    • President, American Association of Physicists in Medicine, Southwest Regional Chapter, 2007
    • Chairman of the Board, American Board of Medical Physics, 2004- 2007
    • Member, Board of Directors, Commission for the Accreditation of Medical Physics Education Programs, 2007- 2010

    Selected Publications:
    Ruan C, Yang SH, PhD, Cusi K, Gao F, Clarke GD. Contrast-enhanced First-pass Myocardial Perfusion MR Imaging with Parallel Acquisition at 3.0 Tesla. Invest Radiol. 2007
    Jun;42(6):352-360.

    Chen H-H, Boykin RD, Clarke GD, Gao J-H, Roby JW III. Routine Testing of Magnetic Field Homogeneity on Clinical MRI Systems. Medical Physics, 2006, 33(11): 4299-4306.

    Ruan C, Yang S, Clarke GD, Amurao MR, Partyka SR, Bradley YC, Cusi K. First-pass Contrast-enhanced Myocardial Perfusion MRI using a Maximum Up-slope Parametric Map. IEEE Trans Information Technology Biomedicine 2006; 10(3):574-580.

    Malik JA, Rubal BJ, Clarke GD, Dick EJ, Ward JA, Harris RA. "Use and Limitations of Magnetic Resonance Phase-Contrast Assessment of Coronary Flow Reserve in a Model of Collateral Dependence" Comparative Medicine 2005 55(4): 317-325.

    Ozus B, Dodd SJ, Clarke GD, Fullerton GD. Orientational Dependence of Intermolecular Double Quantum Coherence (iDQC) Signal From Tendon. Magn Reson Med, 2005; 53(5): 1183- 1186.

    Drost D.J., Riddle W., Clarke G.D. Proton magnetic resonance spectroscopy in the brain: Report of AAPM MR task group #9. Medical Physics 2002; 29: 2177-2197.

    Anderson JA, Wang J, Clarke GD. Choice of phantom material and test protocols to determine radiation exposure rates for fluoroscopy. Radiographics 2000; 20: 1033-1042.

    Hundley WG, Hamilton CA, Clarke GD, Hillis LD, Herrington DM, Lange RA, Applegate RJ, Thomas MA, Payne J, Link KM, Peshock RM. Visualization and functional assessment of proximal and middle left anterior descending coronary stenoses in humans with magnetic resonance imaging. Circulation 1999, 99: 3248-3254.

    Hatab M.R., Giller C.A., Clarke G.D. Evaluation of cerebral arterial flow with transcranial doppler ultrasound: theoretical development and phantom studies. Ultrasound Medicine Biol 1997; 23:1025-1031.

    Clarke G.D., Hundley W.G., McColl R.W., Eckels R., Smith D., Chaney C., Li H-F, Peshock R.M. Velocity-encoded, phase-difference cine MRI measurements of coronary artery flow: dependence on the number of cine frames. J Magn Reson Imag 6:733-742, 1996.

    Contact Information:

    Department of Radiology, Room 652E MED
    University of Texas Health Science Center
    Phone:210-567-5552
    Fax: 210-567-5549
    clarkeg@uthscsa.edu

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